Margaritaria discoidea (Euphorbiaceae) stem bark extract attenuates allergy and Freund′s adjuvant-induced arthritis in rodents

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Anti-inflammatory and analgesic activities of the aqueous extracts of Margaritaria discoidea (Euphorbiaceae) stem bark in experimental animal models.

Margaritaria discoidea is a medicinal plant used for the treatment of various body pains in Central, Eastern and Southern Africa. The aqueous extract of its stem bark was investigated for its anti-inflammatory and analgesic activities in animal models. The extract at 50, 100 and 200mg/kg body weight reduced significantly the formation of oedema induced by carrageenan and histamine. In the aceti...

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Toxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents

Bridelia ferruginea is a woody shrub that grows in the Savannah or rain forests of Africa and has traditionally been used to treat diabetes, arthritis and boils. Despite all these uses, extensive toxicological evaluation has not been carried out. The aim of the present investigation was to evaluate the sub-chronic toxicological effects of the stem bark aqueous extract of Bridelia ferruginea in ...

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Antifungal Screening of Bridelia ferruginea Benth (Euphorbiaceae) Stem Bark Extract in Mouthwash Formulations

The plant Bridelia ferruginea Benth (Euphorbiaceae) has been known for its use in the management of oral thrush ethnomedicinally in various parts of Africa, a practice which has been justified by results of certain scientific studies. The aim of this study was to develop an appropriate dosage formulation, a mouthwash and evaluate the antifungal potential of this dosage formulation against a maj...

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Anti-arthritic Effect of 1'-acetoxychavicol Acetate in Complete Freunds Adjuvant-induced Arthritis in Rats

1'-Acetoxychavicol acetate (ACA) is a phenylpropanoid present in Alpinia galanga (L) Willd syn. Languas galanga. The objective of this study was to isolate 1'-Acetoxychavicol acetate (ACA) from acetone extract of Alpinia galanga (AEAG) and evaluate anti-arthritic activity of 1'-Acetoxychavicol acetate (ACA) and acetone extract of Alpinia galanga (AEAG) on complete Freund’s Adjuvant-induced arth...

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Pharmaceutical Characterization of Aqueous Stem Bark Extract of Bridelia ferruginea Benth (Euphorbiaceae)

Purpose: To characterize some preformulation properties of aqueous stem bark extract of Bridelia ferruginea Benth (Euphorbiaceae) (BF). Methods: The stem bark was extracted by maceration in hot distilled water. Two batches of granules containing the extract were prepared by wet granulation using maize starch, polyvinylpyrrolidone (PVP), Avicel PH-101, magnesium stearate, acacia and lactose as e...

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ژورنال

عنوان ژورنال: Pharmacognosy Research

سال: 2014

ISSN: 0974-8490

DOI: 10.4103/0974-8490.129039